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Dr. Leah Chase-Wallar has been at Hope since 2000.

See Dr. Chase-Wallar's current research 

AREAS OF INTEREST

• Regulation of cystine/glutamate exchange by system x_c^-

EDUCATION

• Ph.D., University of Minnesota, 1999
• B.S., University of Michigan 鈥� Flint, 1993

GRANTS

• Campbell Foundation, 鈥淪tudies of the Regulation of System x_c炉 Activity in a Dopamergic Cell,鈥� 2005鈥�2007
• Towsley Research Scholar Program, 鈥淢echanistic and Regulatory Studies of a Neurotransmitter Transport System,鈥� 2003鈥�2006
• Campbell Foundation, 鈥淩egulation of a Neurotransmitter Transporter by Reactive Oxygen Species,鈥� 2003鈥�2005
• NSF, 鈥淒evelopment of a project-oriented Neuroscience lab at Hope College,鈥� 2002鈥�2003
• NSF-CCLI, 鈥淒evelopment of a project-oriented Neuroscience lab at Hope College,鈥� 2002鈥�2003
• Campbell Foundation, 鈥淢echanistic and regulatory studies of a neurotransmitter transporter,鈥� 2001鈥�2003
• Campbell Foundation, 鈥淢echanistic and regulatory studies of a neurotransmitter transport system,鈥� 2001
• Hope College, Faculty Development Grant, 2001

Published Works

• 鈥淭he Lathyrus Toxin, b-N-oxalyl-L-a,b-diaminoproprionic acid (ODAP) and Homocysteic Acid Sensitize CA1 Pyramidal Neurons to Cystine and L-Amino-6-Phosphonohexanoic Acid,鈥� Toxicology and Applied Pharmacology, 219(1), 2007
• 鈥渓-Quisqualic Acid Transport into Hippocampal Neurons by a l-Cystine-Sensitive Carrier is Required for the Induction of l-Quisqualate Sensitization,鈥� Journal of Neuroscience, 106(2), 2001
• 鈥淎bolition of Quisqualate Sensitization and Enhancement of Potency for Depolarization by Quisqualate in 24-hour Hippocampal Slices briefly exposed to Quisqualate,鈥� Society for Neuroscience, Abst. 26, 2000
• 鈥淒ifferentiation of Two Na+-Independent Glutamate Transport Subtypes in Rat Hippocampal Slices,鈥� Society for Neuroscience, Abst. 25, 1999
• 鈥淓ffects of Quisqualic Acid Analogs on Metabotropic Glutamate Receptors Coupled to Phosphoinositide Hydrolysis in Rat Hippocampus,鈥� Neuropharmacology, 34, 1995
• 鈥淭ype 4a Metabotropic Glutamate Receptor: Identification of New Potent Agonists and Differentiation from the l-(+)2-Amino-4-Phosphonobutanoic Acid Sensitive Receptor in the Lateral Perforant Pathway in Rats,鈥� Molecular Pharmacology, 48, 1995
• 鈥淎spects of Nitrogen and Mineral Nutrition in Icelandic Reindeer, Rangifer tarandus,鈥� Journal of Comparative Biochemistry and Physiology, 109A, 1994

Outside the College

When she鈥檚 not working at Hope, Leah enjoys spending time with her husband, Brad, and their children. In the summer, they enjoy camping, going to the beach and bike riding on Mackinac Island.